malgré or malgré que in French?

Malgré is correct, and takes a NOUN. Malgré que should be avoided in writing: before a clause, use bien que or même si.

Why

Malgré is a preposition: it takes a noun. Malgré que has long been criticised and is still felt to be wrong in writing, even though it is heard. Before a clause, two safe forms: bien que (+ subjunctive) and même si (+ indicative).

malgré

Malgré plusieurs relances, aucune réponse ne m'est parvenue.

Despite several reminders, no reply has reached me.

See the entry : malgré →

malgré que

Bien que j'aie relancé plusieurs fois, aucune réponse ne m'est parvenue.

Although I followed up several times, no reply has reached me.

Form to avoid in writing